Gene Ontology: phagocytosis


phagocytosis (GO:0006909):   (biological_process ontology).

Use to view gene products from Dictyostelium and other species annotated to this GO term as well as to browse the gene ontology.

90 Dictyostelium genes/features have been directly annotated to the term phagocytosis

Gene Reference(s) Evidence
ChLim UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
abpA Rivero, Koppel, Peracino, Bozzaro, Siegert, Weijer, Schleicher, Albrecht & Noegel (1996) ' The role of the cortical cytoskeleton: F-actin crosslinking proteins protect against osmotic stress, ensure cell size, cell shape and motility, and contribute to phagocytosis and development. ' J Cell Sci 109 ( Pt 11) 2679-91
   
IGI
abpC Rivero, Koppel, Peracino, Bozzaro, Siegert, Weijer, Schleicher, Albrecht & Noegel (1996) ' The role of the cortical cytoskeleton: F-actin crosslinking proteins protect against osmotic stress, ensure cell size, cell shape and motility, and contribute to phagocytosis and development. ' J Cell Sci 109 ( Pt 11) 2679-91
   
IGI
act1 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act10 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act11 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act12 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act13 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act14 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act15 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act16 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act17 AgBase, BHF-UCL, dictyBase, HGNC & Roslin Institute and UniProtKB curators. (2011) ' Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. '
   
ISS
act19 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act2 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act20 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act21 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act22 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act24 AgBase, BHF-UCL, dictyBase, HGNC & Roslin Institute and UniProtKB curators. (2011) ' Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. '
   
ISS
act25 AgBase, BHF-UCL, dictyBase, HGNC & Roslin Institute and UniProtKB curators. (2011) ' Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. '
   
ISS
act26 AgBase, BHF-UCL, dictyBase, HGNC & Roslin Institute and UniProtKB curators. (2011) ' Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. '
   
ISS
act27 AgBase, BHF-UCL, dictyBase, HGNC & Roslin Institute and UniProtKB curators. (2011) ' Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. '
   
ISS
act28 AgBase, BHF-UCL, dictyBase, HGNC & Roslin Institute and UniProtKB curators. (2011) ' Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. '
   
ISS
act29 AgBase, BHF-UCL, dictyBase, HGNC & Roslin Institute and UniProtKB curators. (2011) ' Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. '
   
ISS
act3 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act4 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act5 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act6 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act7 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act8 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
act9 Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
aip1 Konzok, Weber, Simmeth, Hacker, Maniak & Muller-Taubenberger (1999) ' DAip1, a Dictyostelium homologue of the yeast actin-interacting protein 1, is involved in endocytosis, cytokinesis, and motility. ' J Cell Biol 146 453-64
   
IMP
alyA Muller, Subert, Otto, Herbst, Ruhling, Maniak & Leippe (2005) ' A Dictyostelium mutant with reduced lysozyme levels compensates by increased phagocytic activity. ' J Biol Chem 280 10435-43
   
IMP
aph1 McMains, Myre, Kreppel & Kimmel (2010) ' Dictyostelium possesses highly diverged presenilin/gamma-secretase that regulates growth and cell-fate specification and can accurately process human APP: a system for functional studies of the presenilin/gamma-secretase complex. ' Dis Model Mech 3 581-94
   
IGI
arcA Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
arcB Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
arcC Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
arcD Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
arcE Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
arpB Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
arpC Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
atg9 Tung, Unal, Ley, Pena, Tunggal, Noegel, Krut, Steinert & Eichinger (2010) ' Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila. ' Cell Microbiol 12 765-80
   
IMP
cbfA Winckler, Trautwein, Tschepke, Neuhauser, Zundorf, Beck, Vogel & Dingermann (2001) ' Gene function analysis by amber stop codon suppression: CMBF is a nuclear protein that supports growth and development of Dictyostelium amoebae. ' J Mol Biol 305 703-14
   
IMP
cdk5 Sharma, Brock, Ammann, DeShazo, Khosla, Gomer & Weeks (2002) ' The cdk5 homologue, crp, regulates endocytosis and secretion in dictyostelium and is necessary for optimum growth and differentiation. ' Dev Biol 247 1-10
   
IMP
chcA O'Halloran & Anderson (1992) ' Clathrin heavy chain is required for pinocytosis, the presence of large vacuoles, and development in Dictyostelium. ' J Cell Biol 118 1371-7
   
IMP
comA Schreiner, Mohrs, Blau-Wasser, von Krempelhuber, Steinert, Schleicher & Noegel (2002) ' Loss of the F-actin binding and vesicle-associated protein comitin leads to a phagocytosis defect. ' Eukaryot Cell 1 906-14
   
IMP
corA Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
Maniak, Rauchenberger, Albrecht, Murphy & Gerisch (1995) ' Coronin involved in phagocytosis: dynamics of particle-induced relocalization visualized by a green fluorescent protein Tag. ' Cell 83 915-24
   
IMP
corB UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
Shina, Unal, Eichinger, Muller-Taubenberger, Schleicher, Steinert & Noegel (2010) ' A Coronin7 homolog with functions in actin-driven processes. ' J Biol Chem 285 9249-61
   
IMP
cshA Huang, Chen, Lo, Liu, Wang & Chang (2004) ' Disruption of the peroxisomal citrate synthase CshA affects cell growth and multicellular development in Dictyostelium discoideum. ' Mol Microbiol 53 81-91
   
IMP
drkC Fang, Brzostowski, Ou, Isik, Nair & Jin (2007) ' A vesicle surface tyrosine kinase regulates phagosome maturation. ' J Cell Biol 178 411-23
   
IMP
dymA Wienke, Knetsch, Neuhaus, Reedy & Manstein (1999) ' Disruption of a dynamin homologue affects endocytosis, organelle morphology, and cytokinesis in Dictyostelium discoideum. ' Mol Biol Cell 10 225-43
   
IMP
dymB Rai, Nothe, Tzvetkov, Korenbaum & Manstein (2010) ' Dictyostelium dynamin B modulates cytoskeletal structures and membranous organelles. ' Cell Mol Life Sci
   
IMP
gefB UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
Wilkins, Chubb & Insall (2000) ' A novel Dictyostelium RasGEF is required for normal endocytosis, cell motility and multicellular development. ' Curr Biol 10 1427-37
   
IMP
gpaB Peracino, Borleis, Jin, Westphal, Schwartz, Wu, Bracco, Gerisch, Devreotes & Bozzaro (1998) ' G protein beta subunit-null mutants are impaired in phagocytosis and chemotaxis due to inappropriate regulation of the actin cytoskeleton. ' J Cell Biol 141 1529-37
   
IMP
ibrA Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
limF UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
lvsA UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
Cornillon, Dubois, Bruckert, Lefkir, Marchetti, Benghezal, De Lozanne, Letourneur & Cosson (2002) ' Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium. ' J Cell Sci 115 737-44
   
IMP
lvsB Cornillon, Dubois, Bruckert, Lefkir, Marchetti, Benghezal, De Lozanne, Letourneur & Cosson (2002) ' Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium. ' J Cell Sci 115 737-44
   
IMP
midA Torija, Vicente, Rodrigues, Robles, Cerdan, Sastre, Calvo & Escalante (2006) ' Functional genomics in Dictyostelium: MidA, a new conserved protein, is required for mitochondrial function and development. ' J Cell Sci 119 1154-64
   
IMP
myoB Clarke, Engel, Giorgione, Muller-Taubenberger, Prassler, Veltman & Gerisch (2010) ' Curvature recognition and force generation in phagocytosis. ' BMC Biol 8 154
   
IEP
Jung, Wu & Hammer (1996) ' Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions. ' J Cell Biol 133 305-23
   
IMP
myoC Jung, Wu & Hammer (1996) ' Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions. ' J Cell Biol 133 305-23
   
IMP
myoD UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
myoE Durrwang, Fujita-Becker, Erent, Kull, Tsiavaliaris, Geeves & Manstein (2006) ' Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis. ' J Cell Sci 119 550-8
   
IMP
myoI Titus (1999) ' A class VII unconventional myosin is required for phagocytosis. ' Curr Biol 9 1297-303
   
IMP
Gebbie, Benghezal, Cornillon, Froquet, Cherix, Malbouyres, Lefkir, Grangeasse, Fache, Dalous, Bruckert, Letourneur & Cosson (2004) ' Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium. ' Mol Biol Cell 15 3915-25
   
IMP
ncstn McMains, Myre, Kreppel & Kimmel (2010) ' Dictyostelium possesses highly diverged presenilin/gamma-secretase that regulates growth and cell-fate specification and can accurately process human APP: a system for functional studies of the presenilin/gamma-secretase complex. ' Dis Model Mech 3 581-94
   
IGI
nramp1 Peracino, Wagner, Balest, Balbo, Pergolizzi, Noegel, Steinert & Bozzaro (2006) ' Function and mechanism of action of Dictyostelium Nramp1 (Slc11a1) in bacterial infection. ' Traffic 7 22-38
   
IEP
nsfA Thompson & Bretscher (2002) ' Cell polarity and locomotion, as well as endocytosis, depend on NSF. ' Development 129 4185-92
   
IMP
p80 UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
pakA Muller-Taubenberger, Bretschneider, Faix, Konzok, Simmeth & Weber (2002) ' Differential localization of the Dictyostelium kinase DPAKa during cytokinesis and cell migration. ' J Muscle Res Cell Motil 23 751-63
   
IMP
pakB UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
phg1A Benghezal, Cornillon, Gebbie, Alibaud, Bruckert, Letourneur & Cosson (2003) ' Synergistic control of cellular adhesion by transmembrane 9 proteins. ' Mol Biol Cell 14 2890-9
   
IMP
phg1B Benghezal, Cornillon, Gebbie, Alibaud, Bruckert, Letourneur & Cosson (2003) ' Synergistic control of cellular adhesion by transmembrane 9 proteins. ' Mol Biol Cell 14 2890-9
   
IMP
phg1c Weijer (2004) ' Dictyostelium morphogenesis. ' Curr Opin Genet Dev 14 392-8
   
TAS
phg2 Gebbie, Benghezal, Cornillon, Froquet, Cherix, Malbouyres, Lefkir, Grangeasse, Fache, Dalous, Bruckert, Letourneur & Cosson (2004) ' Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium. ' Mol Biol Cell 15 3915-25
   
IMP
ppk1 UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
Zhang, Gomez-Garcia, Brown & Kornberg (2005) ' Inorganic polyphosphate in Dictyostelium discoideum: influence on development, sporulation, and predation. ' Proc Natl Acad Sci U S A 102 2731-5
   
IMP
psenB McMains, Myre, Kreppel & Kimmel (2010) ' Dictyostelium possesses highly diverged presenilin/gamma-secretase that regulates growth and cell-fate specification and can accurately process human APP: a system for functional studies of the presenilin/gamma-secretase complex. ' Dis Model Mech 3 581-94
   
IMP
rab21 UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
rab2A Maringer, Saheb & Bush (2014) ' Vesicular Trafficking Defects, Developmental Abnormalities, and Alterations in the Cellular Death Process Occur in Cell Lines that Over-Express Dictyostelium GTPase, Rab2, and Rab2 Mutants. ' Biology (Basel) 3 514-35
   
IMP
rab7A Laurent, Bruckert, Adessi & Satre (1998) ' In vitro reconstituted Dictyostelium discoideum early endosome fusion is regulated by Rab7 but proceeds in the absence of ATP-Mg2+ from the bulk solution. ' J Biol Chem 273 793-9
   
IMP
racG Somesh, Vlahou, Iijima, Insall, Devreotes & Rivero (2006) ' RacG regulates morphology, phagocytosis, and chemotaxis. ' Eukaryot Cell 5 1648-63
   
IDA
racH Somesh, Neffgen, Iijima, Devreotes & Rivero (2006) ' Dictyostelium RacH regulates endocytic vesicular trafficking and is required for localization of vacuolin. ' Traffic 7 1194-212
   
IMP
sadA UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
Froquet, le Coadic, Perrin, Cherix, Cornillon & Cosson (2012) ' TM9/Phg1 and SadA proteins control surface expression and stability of SibA adhesion molecules in Dictyostelium. ' Molecular biology of the cell
   
IMP
Fey, Stephens, Titus & Chisholm (2002) ' SadA, a novel adhesion receptor in Dictyostelium. ' J Cell Biol 159 1109-19
   
IMP
scrA UniProt-GOA (2011) ' Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. '
   
IEA
Seastone, Harris, Temesvari, Bear, Saxe & Cardelli (2001) ' The WASp-like protein scar regulates macropinocytosis, phagocytosis and endosomal membrane flow in Dictyostelium. ' J Cell Sci 114 2673-83
   
IMP
sec7 Muller, Herr, Sukumaran, Omosigho, Plomann, Riyahi, Stumpf, Swaminathan, Tsangarides, Yiannakou, Blau-Wasser, Gallinger, Schleicher, Kolanus & Noegel (2013) ' The cytohesin paralog Sec7 of Dictyostelium discoideum is required for phagocytosis and cell motility. ' Cell Commun. Signal 11 54
   
IMP
shkA Moniakis, Funamoto, Fukuzawa, Meisenhelder, Araki, Abe, Meili, Hunter, Williams & Firtel (2001) ' An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway. ' Genes Dev 15 687-98
   
IMP
sibA Cornillon, Gebbie, Benghezal, Nair, Keller, Wehrle-Haller, Charette, Bruckert, Letourneur & Cosson (2006) ' An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features. ' EMBO Rep 7 617-21
   
IMP
Cornillon, Froquet & Cosson (2008) ' Involvement of Sib proteins in the regulation of cellular adhesion in Dictyostelium discoideum. ' Eukaryot Cell 7 1600-5
   
IMP
sibC Cornillon, Froquet & Cosson (2008) ' Involvement of Sib proteins in the regulation of cellular adhesion in Dictyostelium discoideum. ' Eukaryot Cell 7 1600-5
   
IMP
talA Gebbie, Benghezal, Cornillon, Froquet, Cherix, Malbouyres, Lefkir, Grangeasse, Fache, Dalous, Bruckert, Letourneur & Cosson (2004) ' Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium. ' Mol Biol Cell 15 3915-25
   
IMP
Niewohner, Weber, Maniak, Muller-Taubenberger & Gerisch (1997) ' Talin-null cells of Dictyostelium are strongly defective in adhesion to particle and substrate surfaces and slightly impaired in cytokinesis. ' J Cell Biol 138 349-61
   
IMP
tipD Xiong, Unal, Matthias, Steinert & Eichinger (2015) ' The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions. ' Open Biol 5
   
IMP
torA van Es, Wessels, Soll, Borleis & Devreotes (2001) ' Tortoise, a novel mitochondrial protein, is required for directional responses of Dictyostelium in chemotactic gradients. ' J Cell Biol 152 621-32
   
IMP
trrA Jeong, Choi, Kim, Park & Kang (2006) ' Thioredoxin reductase is required for growth and regulates entry into culmination of Dictyostelium discoideum. ' Mol Microbiol 61 1443-56
   
IMP